Almost 20 years after drug habit despatched him to rehab as a young person, 36-year-old Michael Nalewaja had settled right into a quiet life in Alaska the place he labored as an electrician.
That each one got here crashing down days earlier than Thanksgiving 2025, when he and a mutual good friend unknowingly took a deadly cocktail of fentanyl and carfentanil they could have mistaken for cocaine.
“I heard the phrase ‘post-mortem’ and I actually simply collapsed to the ground,” his mom, Kelley Nalewaja stated, recalling the decision she obtained from his spouse. “Even when any individual had been there ready with Narcan — even when any individual had referred to as 911 in time — he was not going to outlive.”
Carfentanil, a weapons-grade chemical that authorities say is 10,000 instances stronger than morphine and 100 instances stronger than fentanyl, has seen a drastic resurgence throughout the U.S., killing a whole bunch of unsuspecting drug customers.
The rise coincides with a latest crackdown by the Chinese language authorities on the sale of precursors used to make fentanyl. These laws are probably prompting traffickers in Mexico to make use of carfentanil to spice up the efficiency of a weakened model of fentanyl, in accordance with U.S. Drug Enforcement Administration intelligence bulletins reviewed by The Related Press.
The surge of a drug so lethal that lower than a poppy seed-sized quantity can kill an individual comes as fentanyl seizures and total drug overdose deaths proceed a multiyear decline.
“You’re speaking about not even a grain of salt that might be doubtlessly deadly,” stated Frank Tarentino, the DEA’s chief of operations for its northeast area, which stretches from Maine to Virginia. “This presents an especially horrifying proposition for substance abuse dependent individuals who search opioids on the road immediately.”
Carfentanil surge
A decade in the past, carfentanil exploded into the North American drug provide, inflicting a whole bunch of unsuspecting drug customers to overdose, solely to see a significant dip after China banned it, closing a key regulatory loophole within the U.S.
However the state of affairs has shifted dramatically in recent times.
In 2025, DEA labs recognized carfentanil 1,400 instances in U.S. drug seizures, in contrast with 145 in 2023 and solely 54 in 2022, in accordance with DEA information seen by AP.
Traffickers in Mexico could also be experimenting with producing carfentanil themselves, authorities say, whereas others might be procuring it from China-based distributors skirting the nation’s laws by spamming on-line boards in different nations with adverts for the drug.
Complicating issues for the cartels are the acute risks related to manufacturing carfentanil, Tarentino stated.
“You’ll be able to’t simply dabble on this,” he stated. “This isn’t some mad scientist on Reddit you’re going to get to exit to a rudimentary laboratory in Mexico to make carfentanil.”
Dip in overdose deaths and fentanyl seizures
U.S. overdose deaths have fallen for greater than two years — the longest drop in many years. Consultants level to a number of doable explanations, together with the overdose-reversing drug naloxone being extra extensively accessible and the enlargement of habit remedy. Some have additionally tied it to the regulatory adjustments the U.S. has pressed for in China.
Consultants say that even a number of excessive doses of naloxone won’t be sufficient to reverse an overdose when carfentanil is concerned.
Fentanyl seizures, together with a number of different illicit medication, have additionally dipped. U.S. Customs and Border Safety reported that fentanyl seizures plunged to about 12,000 kilos (5,443 kilograms) in 2025 — lower than half the quantity seized in 2023.
However at the same time as fentanyl numbers fall, it stays a significant focus of the DEA. Only recently, the company’s proposed funds included a $362 million enhance centered on cartel-driven fentanyl trafficking.
“Anybody who takes a capsule that’s not prescribed to them by their physician is taking part in a recreation of Russian roulette with their life,” stated Sara Carter, President Donald Trump’s drug czar. “But when these terrorists suppose they’ll proceed this chemical warfare with out penalties, they’re unsuitable.”
Researched as a chemical weapon
Whereas the prevalence of carfentanil nonetheless pales compared to fentanyl, consultants are nonetheless alarmed by the rise of a substance researched for years as a chemical weapon and deployed by Russian forces on Chechen separatists in 2002.
The DEA’s annual quota for lawfully manufactured carfentanil — veterinarians use it to tranquilize elephants and different massive animals — is simply 20 grams, an quantity that may match within the palm of your hand.
“It’s like a organic weapon,” stated Michael King Jr., founding father of the Opioid Consciousness Basis. “If the world thinks we had an issue with fentanyl, that’s minute in comparison with what we’re going to be coping with with carfentanil.”
In 2024, overdose deaths involving carfentanil almost tripled in comparison with the earlier 12 months, with 413 deaths throughout 42 states and Washington, D.C., in accordance with the newest information accessible by the Facilities for Illness Management and Prevention.
“Carfentanil undoubtedly has that potential of spreading all through the US until legislation enforcement actually focuses in on carfentanil and so they develop intelligence as to how these drug addicts are getting it,” stated Mike Vigil, a former chief of worldwide operations on the DEA.
In latest months, the DEA has documented a number of massive seizures of carfentanil. In October, the DEA Los Angeles Field Division discovered 628,000 capsules containing carfentanil, whereas in September, officers seized greater than 50,000 counterfeit M30 capsules from an individual at a gas station in Washington state that turned out to be a mix of carfentanil and acetaminophen.
‘All about cash’
In some circumstances, frequent drug customers have turn out to be tolerant to fentanyl and are in search of out carfentanil, regardless of the hazard, due to the sudden euphoria it guarantees, defined Rob Tanguay, senior medical lead for habit companies with Restoration Alberta, a well being company in Canada. It appeals to the drug market, he stated, as a result of so little of it goes such a great distance towards provide.
“The hardest half about all of this,” he stated, “is that that is all about cash.”
After Michael Nalewaja’s demise, his mom determined in opposition to a big funeral.
As a substitute, she organized a city corridor in her hometown of El Dorado Hills, California, bringing collectively native officers together with moms who had gone by means of one thing comparable.
As she grieves her son, an adept salesman stuffed with charisma who had lately gotten a nationwide award by {the electrical} union, she’s pushing for main legislative and judicial adjustments so others don’t undergo what she did due to a drug she stated was by no means meant for people.
“It’s not an OD; it’s not an overdose,” she stated. “It’s a homicide weapon.”
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Related Press author Joshua Goodman in Miami contributed.
Hallie Golden And Jim Mustian, The Related Press